Docking Viva Questions: 20 Things Your Examiner Will Ask

By BioDockify Computational Research Team · October 11, 2026 · Student Guides

The 20 docking questions examiners actually ask in vivas and defenses - target choice, grid, scores, controls, statistics, limitations - each with what a strong answer contains and the trap it is guarding against.

Read the complete article with tables, code and references on BioDockify.

Key References

• Trott, O. & Olson, A.J. AutoDock Vina. J. Comput. Chem. 31, 445-461 (2010). DOI: 10.1002/jcc.21334
• Wasserstein, R.L. & Lazar, N.A. The ASA statement on p-values. Am. Stat. 70, 129-133 (2016). DOI: 10.1080/00031305.2016.1154108
• Lipinski, C.A. et al. Experimental and computational approaches to estimate solubility and permeability. Adv. Drug Deliv. Rev. 23, 3-25 (1997). DOI: 10.1016/S0169-409X(96)00423-1

Scope & Limitations

Examiners vary by field and temperament; treat the 20 as the high-probability core, not an exhaustive script The strongest viva answers cite your own run data - no generic answer beats a specific, stamped result