SwissTargetPrediction Alternative for Alzheimer Targets
By BioDockify Computational Research Team · September 5, 2026 · Tools
A SwissTargetPrediction alternative for Alzheimer researchers: one-step AChE, BACE1 and GSK-3b inhibitor prediction from SMILES with CNS MPO descriptors and batch screening.
Read the complete article with tables, code and references on BioDockify.
Key References
- Gfeller D, Michielin O, Zoete V. Shaping the interaction landscape of bioactive molecules. Bioinformatics. 2013;29(23):3073-3079.
- Daina A, Michielin O, Zoete V. SwissTargetPrediction: updated data and new features. Nucleic Acids Res. 2019;47(W1):W357-W364. doi:10.1093/nar/gkz382
- Cavalli A, Bolognesi ML, Minarini A, et al. Multi-target-directed ligands to combat neurodegenerative diseases. J Med Chem. 2008;51(3):347-372.
Scope & Limitations
Target-fishing servers and MTDL predictors answer different questions; this comparison covers the Alzheimer MTDL workflow specifically, and every computational prediction still requires docking, MD and experimental validation